Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_3570PFAM: N-6 DNA methylase; KEGG: mma:MM_2981 type I restriction-modification system specificity subunit. (647 aa)    
Predicted Functional Partners:
Msil_3571
KEGG: mca:MCA0277 hypothetical protein.
 
 0.995
Msil_1551
KEGG: rde:RD1_4054 type I restriction-mod.
 
 
 0.976
Msil_1553
PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: lpc:LPC_2788 putative type I restriction enzyme R protein.
 
  
 0.919
Msil_3575
PFAM: type III restriction protein res subunit; protein of unknown function DUF450; SMART: DEAD-like helicases; KEGG: mma:MM_2976 type I restriction-modification system restriction subunit.
 
  
 0.919
Msil_3573
KEGG: pla:Plav_2928 hypothetical protein.
       0.785
Msil_3572
Hypothetical protein.
       0.773
Msil_3569
Prevent-host-death family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
       0.668
Msil_0829
KEGG: dsh:Dshi_0990 putative DNA helicase related protein.
  
  
 0.636
guaA
GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP.
     
 0.488
Msil_2723
Beta-ketoacyl synthase; PFAM: short-chain dehydrogenase/reductase SDR; phosphopantetheine-binding; Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; Methyltransferase type 12; KR domain protein; Beta-ketoacyl synthase; Acyl transferase; KEGG: bid:Bind_1113 beta-ketoacyl synthase.
   
 
 0.409
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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