Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Msil_3763PFAM: nickel-dependent hydrogenase large subunit; KEGG: bbt:BBta_0461 uptake hydrogenase large subunit. (532 aa)    
Predicted Functional Partners:
Msil_3764
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: bbt:BBta_0460 uptake hydrogenase accessory protein HupU.
 
 0.999
Msil_3760
TIGRFAM: hydrogenase maturation protease; PFAM: peptidase M52 hydrogen uptake protein; KEGG: npu:Npun_F0374 hydrogenase maturation protease.
 
 
 0.927
Msil_2749
Hydrogen dehydrogenase; PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: hch:HCH_00106 coenzyme F420-reducing hydrogenase, gamma subunit.
  
 
 0.861
Msil_3758
KEGG: bbt:BBta_0466 hypothetical protein.
 
     0.861
Msil_3755
PFAM: nitrogen-fixing NifU domain protein; Rieske [2Fe-2S] domain protein; KEGG: bbt:BBta_0469 putative nitrogen-fixing NifU, Rieske (2Fe-2S) region.
 
   
 0.853
Msil_3752
TIGRFAM: hydrogenase assembly chaperone hypC/hupF; PFAM: hydrogenase expression/formation protein (HUPF/HYPC); KEGG: ter:Tery_0794 hydrogenase assembly chaperone HypC/HupF.
 
 
 0.835
Msil_3754
PFAM: NHL repeat containing protein; KEGG: bbt:BBta_0470 hypothetical protein.
 
     0.832
hypA-2
Hydrogenase expression/synthesis HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
 
 0.815
Msil_3751
TIGRFAM: hydrogenase expression/formation protein HypD; PFAM: hydrogenase formation HypD protein; KEGG: bbt:BBta_0474 hydrogenase expression/formation; Belongs to the HypD family.
 
 
 0.748
hypA
Hydrogenase nickel insertion protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
  
 
 0.686
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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