Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
Msil_3875PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: bid:Bind_3031 glutamate synthase (ferredoxin). (1566 aa)    
Predicted Functional Partners:
Msil_2986
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: pzu:PHZ_p0135 NADPH-dependent glutamate synthase beta chain.
 
 0.999
Msil_3874
TIGRFAM: glutamate synthase, NADH/NADPH, small subunit; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: bid:Bind_3032 glutamate synthase, NADH/NADPH, small subunit.
 0.999
carB
TIGRFAM: carbamoyl-phosphate synthase, large subunit; PFAM: Carbamoyl-phosphate synthase L chain ATP-binding; Carbamoyl-phosphate synthetase large chain oligomerisation; Carbamoyl-phosphate synthetase large chain domain protein; MGS domain protein; KEGG: bid:Bind_0869 carbamoyl-phosphate synthase, large subunit; Belongs to the CarB family.
  
 
 0.969
Msil_0426
Glutamate--ammonia ligase; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: mrd:Mrad2831_5128 glutamate--ammonia ligase.
  
 
 0.964
Msil_0427
TIGRFAM: glutamine synthetase, type I; PFAM: glutamine synthetase catalytic region; glutamine synthetase beta-Grasp; KEGG: bid:Bind_1216 glutamine synthetase, type I.
  
 
 0.964
Msil_2635
TIGRFAM: glutamine synthetase, type III; PFAM: glutamine synthetase catalytic region; KEGG: rpb:RPB_1135 glutamate--ammonia ligase.
  
 
 0.964
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.963
Msil_2961
PFAM: aminotransferase class I and II; KEGG: bid:Bind_0079 aminotransferase class I and II.
  
 
 0.962
Msil_1659
Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family.
  
 
 0.944
glsA
PFAM: Glutaminase, core; KEGG: yen:YE2500 glutaminase; Belongs to the glutaminase family.
     
 0.942
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
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