Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Msil_3904Integral membrane sensor hybrid histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: bja:blr2697 VirA-like protein. (829 aa)    
Predicted Functional Partners:
Msil_3903
PFAM: Di-haem cytochrome c peroxidase; KEGG: bja:blr2696 cytochrome c peroxidase.
 
     0.799
Msil_0520
Transketolase central region; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.
   
 0.798
Msil_1887
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; response regulator receiver; KEGG: lch:Lcho_0045 adenylate/guanylate cyclase.
 
 
 0.683
Msil_3900
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bja:blr2694 VirG-like two component response regulator.
 
 
 0.666
Msil_2794
PFAM: response regulator receiver; KEGG: rpb:RPB_4041 response regulator receiver domain protein.
  
 
   0.651
Msil_3741
PFAM: response regulator receiver; KEGG: rpd:RPD_3796 response regulator receiver.
 
 
 
 0.590
Msil_3208
Multi-sensor hybrid histidine kinase; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; CHASE3 domain protein; KEGG: swi:Swit_4726 multi-sensor hybrid histidine kinase.
 
 
 
0.547
Msil_0423
PFAM: response regulator receiver; KEGG: bid:Bind_1212 response regulator receiver protein.
  
 
   0.528
Msil_0850
PFAM: response regulator receiver; KEGG: rpc:RPC_1228 response regulator receiver domain protein (CheY-like).
  
 
   0.518
Msil_2529
Two component transcriptional regulator, winged helix family; PFAM: response regulator receiver; transcriptional regulator domain protein; KEGG: bid:Bind_0344 two component transcriptional regulator, winged helix family.
 
 
 0.518
Your Current Organism:
Methylocella silvestris
NCBI taxonomy Id: 395965
Other names: M. silvestris BL2, Methylocella silvestris BL2, Methylocella silvestris str. BL2, Methylocella silvestris strain BL2, Methylocella sp. BL2
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.