STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ubiEBifunctional 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase/demethylmenaquinone methyltransferase; Methyltransferase required for the conversion of demethylmenaquinol (DMKH2) to menaquinol (MKH2) and the conversion of 2-polyprenyl-6-methoxy-1,4-benzoquinol (DDMQH2) to 2-polyprenyl-3- methyl-6-methoxy-1,4-benzoquinol (DMQH2). (258 aa)    
Predicted Functional Partners:
ANL61560.1
2-octaprenyl-6-methoxyphenyl hydroxylase protein; Protein involved in oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen, flavin adenine dinucleotide binding, ubiquinone biosynthetic process and oxidation-reduction process.
  
 
 0.929
ANL59475.1
Ubiquinone biosynthesis hydroxylase protein; Protein involved in oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen, flavin adenine dinucleotide binding, ubiquinone biosynthetic process and oxidation-reduction process.
  
 
 0.927
ANL60055.1
Ubiquinone biosynthesis family protein; Protein involved in oxidoreductase activity, transition metal ion binding, ubiquinone biosynthetic process and oxidation-reduction process; Belongs to the COQ7 family.
  
 
 0.917
ubiG
Bifunctional 3-demethylubiquinol 3-O-methyltransferase/2-octaprenyl-6-hydroxyphenyl methylase; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the methyltransferase superfamily. UbiG/COQ3 family.
 
 
 0.806
ubiB
Ubiquinone biosynthesis protein UbiB; Is probably a protein kinase regulator of UbiI activity which is involved in aerobic coenzyme Q (ubiquinone) biosynthesis. Belongs to the ABC1 family. UbiB subfamily.
 
  
 0.726
ubiA
UbiA prenyltransferase family protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate.
 
   
 0.701
mutM
Bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
 
   
 0.648
rpsU-1
30S ribosomal protein S21 1; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS21 family.
      
 0.623
rpsU-2
30S ribosomal protein S21 2; Protein involved in structural constituent of ribosome and translation; Belongs to the bacterial ribosomal protein bS21 family.
      
 0.623
fadB
enoyl-CoA hydratase; Protein involved in catalytic activity and metabolic process; Belongs to the enoyl-CoA hydratase/isomerase family.
       0.533
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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