| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL57544.1 | hrpB | AMC85_CH00100 | AMC85_CH00060 | Protein involved in nucleic acid binding, 3'-5' exonuclease activity and nucleobase-containing compound metabolic process. | ATP-dependent RNA helicase HrpB; Protein involved in nucleic acid binding, ATP binding and ATP-dependent helicase activity. | 0.915 |
| ANL57544.1 | rnr | AMC85_CH00100 | AMC85_CH01706 | Protein involved in nucleic acid binding, 3'-5' exonuclease activity and nucleobase-containing compound metabolic process. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.915 |
| ANL57544.1 | rph | AMC85_CH00100 | AMC85_CH00401 | Protein involved in nucleic acid binding, 3'-5' exonuclease activity and nucleobase-containing compound metabolic process. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.979 |
| ANL57544.1 | rpsA | AMC85_CH00100 | AMC85_CH00102 | Protein involved in nucleic acid binding, 3'-5' exonuclease activity and nucleobase-containing compound metabolic process. | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.941 |
| ANL57544.1 | rpsD | AMC85_CH00100 | AMC85_CH02404 | Protein involved in nucleic acid binding, 3'-5' exonuclease activity and nucleobase-containing compound metabolic process. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.956 |
| ANL57544.1 | rpsK | AMC85_CH00100 | AMC85_CH01774 | Protein involved in nucleic acid binding, 3'-5' exonuclease activity and nucleobase-containing compound metabolic process. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.954 |
| ANL57831.1 | ANL57832.1 | AMC85_CH00398 | AMC85_CH00399 | Coproporphyrinogen III oxidase HemN-like protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.931 |
| ANL57831.1 | rph | AMC85_CH00398 | AMC85_CH00401 | Coproporphyrinogen III oxidase HemN-like protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.823 |
| ANL57832.1 | ANL57831.1 | AMC85_CH00399 | AMC85_CH00398 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Coproporphyrinogen III oxidase HemN-like protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.931 |
| ANL57832.1 | rph | AMC85_CH00399 | AMC85_CH00401 | Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.989 |
| dnaG | rph | AMC85_CH03111 | AMC85_CH00401 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.913 |
| dnaG | rpsK | AMC85_CH03111 | AMC85_CH01774 | DNA primase; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.586 |
| hrpB | ANL57544.1 | AMC85_CH00060 | AMC85_CH00100 | ATP-dependent RNA helicase HrpB; Protein involved in nucleic acid binding, ATP binding and ATP-dependent helicase activity. | Protein involved in nucleic acid binding, 3'-5' exonuclease activity and nucleobase-containing compound metabolic process. | 0.915 |
| hrpB | rnd | AMC85_CH00060 | AMC85_CH01554 | ATP-dependent RNA helicase HrpB; Protein involved in nucleic acid binding, ATP binding and ATP-dependent helicase activity. | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | 0.938 |
| hrpB | rph | AMC85_CH00060 | AMC85_CH00401 | ATP-dependent RNA helicase HrpB; Protein involved in nucleic acid binding, ATP binding and ATP-dependent helicase activity. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.855 |
| hrpB | rpsA | AMC85_CH00060 | AMC85_CH00102 | ATP-dependent RNA helicase HrpB; Protein involved in nucleic acid binding, ATP binding and ATP-dependent helicase activity. | 30S ribosomal protein S1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence. | 0.935 |
| hrpB | rpsD | AMC85_CH00060 | AMC85_CH02404 | ATP-dependent RNA helicase HrpB; Protein involved in nucleic acid binding, ATP binding and ATP-dependent helicase activity. | 30S ribosomal protein S4; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit. | 0.957 |
| hrpB | rpsK | AMC85_CH00060 | AMC85_CH01774 | ATP-dependent RNA helicase HrpB; Protein involved in nucleic acid binding, ATP binding and ATP-dependent helicase activity. | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. | 0.908 |
| rnd | hrpB | AMC85_CH01554 | AMC85_CH00060 | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | ATP-dependent RNA helicase HrpB; Protein involved in nucleic acid binding, ATP binding and ATP-dependent helicase activity. | 0.938 |
| rnd | rnr | AMC85_CH01554 | AMC85_CH01706 | Ribonuclease D; Exonuclease involved in the 3' processing of various precursor tRNAs. Initiates hydrolysis at the 3'-terminus of an RNA molecule and releases 5'-mononucleotides; Belongs to the RNase D family. | Ribonuclease R; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.960 |