Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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bchEMg-protoporphyrin IX monomethyl ester (oxidative) cyclase; Protein involved in oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen, NADP binding, chlorophyll biosynthetic process and oxidation-reduction process. (509 aa)    
Predicted Functional Partners:
hemF
coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
      
 0.813
ANL57898.1
methylated-DNA--protein-cysteine S-methyltransferase protein; Protein involved in sequence-specific DNA binding transcription factor activity, sequence-specific DNA binding, zinc ion binding and regulation of transcription, DNA-dependent.
       0.631
ANL57899.1
Phosphonoenolpyruvate phosphonomutase protein; Protein involved in catalytic activity.
       0.603
ANL57559.1
Protein involved in polyphosphate kinase activity and phosphorus metabolic process.
   
    0.509
ANL57980.1
Protein involved in polyphosphate kinase activity and phosphorus metabolic process.
   
    0.509
ANL57896.1
Protein involved in hydrolase activity.
       0.503
ANL58740.1
HSP20 family heat shock protein; Belongs to the small heat shock protein (HSP20) family.
   
    0.493
ANL57831.1
Coproporphyrinogen III oxidase HemN-like protein; Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family.
  
  
 0.450
ispDF
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase; Bifunctional enzyme that catalyzes the formation of 4- diphosphocytidyl-2-C-methyl-D-erythritol from CTP and 2-C-methyl-D- erythritol 4-phosphate (MEP) (IspD), and catalyzes the conversion of 4- diphosphocytidyl-2-C-methyl-D-erythritol 2-phosphate (CDP-ME2P) to 2-C- methyl-D-erythritol 2,4-cyclodiphosphate (ME-CPP) with a corresponding release of cytidine 5-monophosphate (CMP) (IspF).
     
 0.438
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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