STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrEOrotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (229 aa)    
Predicted Functional Partners:
pyrF
Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily.
 
 
 0.998
pyrD
Dihydroorotate dehydrogenase (quinone); Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
 0.988
pyrB
Aspartate carbamoyltransferase catalytic subunit; Protein involved in carboxyl- or carbamoyltransferase activity and cellular amino acid metabolic process; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
  
 0.972
carA
Carbamoyl phosphate synthetase small subunit; Belongs to the CarA family.
 
  
 0.947
carB
Carbamoyl phosphate synthetase large subunit; Protein involved in ATP binding, ligase activity and nitrogen compound metabolic process; Belongs to the CarB family.
 
 
 0.914
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
  
 
 0.879
ANL58992.1
Carbamoyl phosphate synthetase large subunit protein; Protein involved in ATP binding and ligase activity.
  
 
 0.869
preA
Dihydropyrimidine dehydrogenase subunit PreA; Protein involved in electron carrier activity, iron-sulfur cluster binding, UMP biosynthetic process and oxidation-reduction process.
  
 
 0.869
ANL57822.1
Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds.
 
  
 0.855
pyrC-2
Dihydroorotase 2; Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds.
 
  
 0.852
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.