Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
frkFructokinase; Protein involved in phosphotransferase activity, alcohol group as acceptor. (308 aa)    
Predicted Functional Partners:
mtlK
Protein involved in mannitol-1-phosphate 5-dehydrogenase activity, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding and oxidation-reduction process.
 
  
 0.975
pgi
Protein involved in glucose-6-phosphate isomerase activity, gluconeogenesis and glycolysis; Belongs to the GPI family.
  
 
 0.954
xylA
Protein involved in xylose isomerase activity and carbohydrate metabolic process; Belongs to the xylose isomerase family.
    
 0.946
glmS
Glucosamine--fructose-6-phosphate aminotransferase (isomerizing); Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
     
 0.943
pfp
Pyrophosphate--fructose-6-phosphate 1-phosphotransferase protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
  
 0.938
aglA
Alpha-glucosidase; Protein involved in catalytic activity, cation binding and carbohydrate metabolic process.
 
  
 0.929
ANL60594.1
Alpha amylase protein; Protein involved in catalytic activity, cation binding and carbohydrate metabolic process.
 
  
 0.929
ANL61627.1
Protein involved in sugar binding and carbohydrate metabolic process.
  
 
 0.911
ANL57487.1
Protein involved in phosphoenolpyruvate-dependent sugar phosphotransferase system.
    
 0.816
ANL57966.1
Aldo/keto reductase protein.
    
  0.801
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.