Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
otsAAlpha,alpha-trehalose-phosphate synthase (UDP-forming); Probably involved in the osmoprotection via the biosynthesis of trehalose. Catalyzes the transfer of glucose from UDP-alpha-D- glucose (UDP-Glc) to D-glucose 6-phosphate (Glc-6-P) to form trehalose- 6-phosphate. Acts with retention of the anomeric configuration of the UDP-sugar donor; Belongs to the glycosyltransferase 20 family. (468 aa)    
Predicted Functional Partners:
exoN
UTP-glucose-1-phosphate uridylyltransferase; Protein involved in nucleotidyltransferase activity and biosynthetic process.
    
 0.926
ANL59012.1
Cellulose synthase subunit CelA protein; Protein involved in cyclic-di-GMP binding and UDP-glucose metabolic process.
  
 
 0.908
treS
Trehalose synthase; Protein involved in catalytic activity, cation binding and carbohydrate metabolic process.
 
  
 0.906
glgC
Glucose-1-phosphate adenylyltransferase; Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc; Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.
    
 0.881
lpsL
UDP-glucuronate 5'-epimerase; Protein involved in nucleotide binding, coenzyme binding and carbohydrate metabolic process.
     
  0.800
ANL60302.1
Serine-protein kinase PrkA family protein.
   
    0.646
ANL61012.1
Hypothetical protein.
   
    0.614
betA
Choline dehydrogenase; Involved in the biosynthesis of the osmoprotectant glycine betaine. Catalyzes the oxidation of choline to betaine aldehyde and betaine aldehyde to glycine betaine at the same rate.
      
 0.599
osmC
Osmotically inducible peroxiredoxin OsmC; Protein involved in response to stress.
   
    0.516
gltB
Glutamate synthase (NADPH) large subunit; Protein involved in catalytic activity, oxidoreductase activity, acting on the CH-NH2 group of donors, nitrogen compound metabolic process and oxidation-reduction process.
  
   
 0.507
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
Server load: low (36%) [HD]