STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pgiProtein involved in glucose-6-phosphate isomerase activity, gluconeogenesis and glycolysis; Belongs to the GPI family. (541 aa)    
Predicted Functional Partners:
pfp
Pyrophosphate--fructose-6-phosphate 1-phosphotransferase protein; Catalyzes the phosphorylation of D-fructose 6-phosphate, the first committing step of glycolysis. Uses inorganic phosphate (PPi) as phosphoryl donor instead of ATP like common ATP-dependent phosphofructokinases (ATP-PFKs), which renders the reaction reversible, and can thus function both in glycolysis and gluconeogenesis. Consistently, PPi-PFK can replace the enzymes of both the forward (ATP- PFK) and reverse (fructose-bisphosphatase (FBPase)) reactions.
 
 0.993
tpiA-1
Triosephosphate isomerase 1; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family.
  
 0.992
pgm
Phosphoglucomutase; Protein involved in intramolecular transferase activity, phosphotransferases and carbohydrate metabolic process.
  
 0.991
ANL61050.1
Protein involved in pyruvate kinase activity, potassium ion binding and glycolysis; Belongs to the pyruvate kinase family.
 
 
 0.989
gap
Glyceraldehyde 3-phosphate dehydrogenase; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, NADP binding, NAD binding and oxidation-reduction process; Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.
 
 
 0.985
cbbT
Transketolase; Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
  
 0.984
eno-1
Enolase 1; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 0.980
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
 
 0.977
zwf-1
Glucose-6-phosphate 1-dehydrogenase 1; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.976
zwf-2
Glucose-6-phosphate 1-dehydrogenase 2; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
  
 
 0.976
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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