STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metZO-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide. (394 aa)    
Predicted Functional Partners:
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.981
cysK
Protein involved in cysteine synthase activity, pyridoxal phosphate binding and cysteine biosynthetic process from serine.
 
 0.980
cysB
Cysteine synthase; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process.
 
 0.980
metA
Homoserine O-succinyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine; Belongs to the MetA family.
 
 
 0.967
ANL59046.1
O-acetylhomoserine aminocarboxypropyltransferase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process.
 
 
0.937
ANL59473.1
Protein involved in oxidoreductase activity, heme binding, iron-sulfur cluster binding and oxidation-reduction process.
  
 0.935
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.927
metC
Cystathionine beta-lyase; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process.
  
  
 
0.923
hom-1
Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process.
 
 
 0.903
sseA
3-mercaptopyruvate sulfurtransferase.
 
 
 0.848
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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