Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
mscLLarge-conductance mechanosensitive channel; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell. (145 aa)    
Predicted Functional Partners:
metK
S-adenosylmethionine synthetase; Protein involved in methionine adenosyltransferase activity, ATP binding and S-adenosylmethionine biosynthetic process; Belongs to the AdoMet synthase family.
  
    0.853
ribH-1
6,7-dimethyl-8-ribityllumazine synthase 1; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.853
ribH-2
6,7-dimethyl-8-ribityllumazine synthase 2; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin.
  
  
 0.853
mscS
Small-conductance mechanosensitive channel; Protein involved in transmembrane transport.
     
 0.830
ANL58035.1
Sensor histidine kinase/response regulator hybrid protein; Protein involved in signal transducer activity, protein histidine kinase activity, signal transduction and peptidyl-histidine phosphorylation.
     
 0.728
kefB
Glutathione-regulated potassium-efflux transporter protein KefB; Protein involved in nucleotide binding, cation transport and transmembrane transport; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family.
     
 0.725
proB
Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.
     
 0.682
dppD
Dipeptide ABC transporter ATP-binding protein DppD; Protein involved in ATP binding, ATPase activity and peptide transport; Belongs to the ABC transporter superfamily.
      
 0.661
nrdF
Ribonucleotide-diphosphate reductase subunit beta; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family.
     
 0.631
ndvA
Beta-1,2-glucan ABC transporter ATP-binding/permease protein NdvA; Involved in Beta-(1-->2)glucan export. Transmembrane domains (TMD) form a pore in the inner membrane and the ATP-binding domain (NBD) is responsible for energy generation.
     
 0.614
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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