Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
eddPhosphogluconate dehydratase; Catalyzes the dehydration of 6-phospho-D-gluconate to 2- dehydro-3-deoxy-6-phospho-D-gluconate; Belongs to the IlvD/Edd family. (607 aa)    
Predicted Functional Partners:
pgl
6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.
 
 
 0.997
eda
Bifunctional 2-keto-4-hydroxyglutarate aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase; Protein involved in catalytic activity.
 
 
 0.991
zwf-1
Glucose-6-phosphate 1-dehydrogenase 1; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
 0.981
zwf-2
Glucose-6-phosphate 1-dehydrogenase 2; Catalyzes the oxidation of glucose 6-phosphate to 6- phosphogluconolactone.
 
  
 0.943
idnK-1
Gluconokinase 1; Protein involved in kinase activity, ATP binding and carbohydrate metabolic process.
  
 
 0.933
kdgK
2-dehydro-3-deoxygluconokinase.
    
 0.923
gnd
6-phosphogluconate dehydrogenase (decarboxylating); Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.
   
 0.921
ANL60990.1
6-phosphogluconate dehydrogenase-related protein; Protein involved in nucleotide binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding and oxidation-reduction process.
     
 0.921
glk
Glucokinase; Protein involved in glucokinase activity, ATP binding, glycolysis and glucose 6-phosphate metabolic process; Belongs to the bacterial glucokinase family.
 
  
 0.905
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.747
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
Server load: low (40%) [HD]