Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
thrBHomoserine kinase; Protein involved in transferase activity, transferring phosphorus-containing groups; Belongs to the pseudomonas-type ThrB family. (321 aa)    
Predicted Functional Partners:
hom-1
Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process.
 
  
 0.937
thrC
Protein involved in threonine synthase activity, pyridoxal phosphate binding and threonine biosynthetic process.
    
 0.925
rnhA
Ribonuclease H; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.
       0.824
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.815
ANL59046.1
O-acetylhomoserine aminocarboxypropyltransferase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process.
    
  0.809
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.804
ANL58689.1
Aminotransferase class 4 protein; Protein involved in catalytic activity and metabolic process.
     
 0.804
ilvE
Protein involved in branched-chain-amino-acid transaminase activity and branched chain family amino acid metabolic process.
     
 0.804
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
 0.803
metC
Cystathionine beta-lyase; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process.
     
 0.803
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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