STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thrBHomoserine kinase; Protein involved in transferase activity, transferring phosphorus-containing groups; Belongs to the pseudomonas-type ThrB family. (321 aa)    
Predicted Functional Partners:
hom-1
Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process.
 
  
 0.934
thrC
Protein involved in threonine synthase activity, pyridoxal phosphate binding and threonine biosynthetic process.
    
 0.923
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.814
ANL59046.1
O-acetylhomoserine aminocarboxypropyltransferase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process.
    
  0.809
ANL58689.1
Aminotransferase class 4 protein; Protein involved in catalytic activity and metabolic process.
     
 0.807
ilvE
Protein involved in branched-chain-amino-acid transaminase activity and branched chain family amino acid metabolic process.
     
 0.807
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
    
  0.803
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
     
  0.800
metC
Cystathionine beta-lyase; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process.
     
  0.800
cysE-1
Serine O-acetyltransferase 1; Protein involved in transferase activity and cysteine biosynthetic process from serine.
     
  0.800
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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