| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL61044.1 | ANL61686.1 | AMC85_CH03710 | AMC85_CH04367 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | 0.943 |
| ANL61044.1 | ilvA | AMC85_CH03710 | AMC85_CH01850 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.924 |
| ANL61044.1 | ltaE | AMC85_CH03710 | AMC85_CH03743 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Low-specificity threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.912 |
| ANL61044.1 | tdh | AMC85_CH03710 | AMC85_CH03108 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.904 |
| ANL61044.1 | thrC | AMC85_CH03710 | AMC85_CH01049 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Protein involved in threonine synthase activity, pyridoxal phosphate binding and threonine biosynthetic process. | 0.949 |
| ANL61686.1 | ANL61044.1 | AMC85_CH04367 | AMC85_CH03710 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | 0.943 |
| ANL61686.1 | hom-1 | AMC85_CH04367 | AMC85_CH01968 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process. | 0.850 |
| ANL61686.1 | ilvA | AMC85_CH04367 | AMC85_CH01850 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.925 |
| ANL61686.1 | ltaE | AMC85_CH04367 | AMC85_CH03743 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Low-specificity threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.912 |
| ANL61686.1 | tdh | AMC85_CH04367 | AMC85_CH03108 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | L-threonine 3-dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of L-threonine to 2- amino-3-ketobutyrate; Belongs to the zinc-containing alcohol dehydrogenase family. | 0.904 |
| ANL61686.1 | thrB | AMC85_CH04367 | AMC85_CH01032 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Homoserine kinase; Protein involved in transferase activity, transferring phosphorus-containing groups; Belongs to the pseudomonas-type ThrB family. | 0.803 |
| ANL61686.1 | thrC | AMC85_CH04367 | AMC85_CH01049 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Protein involved in threonine synthase activity, pyridoxal phosphate binding and threonine biosynthetic process. | 0.961 |
| hom-1 | ANL61686.1 | AMC85_CH01968 | AMC85_CH04367 | Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process. | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | 0.850 |
| hom-1 | lysC | AMC85_CH01968 | AMC85_CH03939 | Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process. | Protein involved in aspartate kinase activity and lysine biosynthetic process via diaminopimelate; Belongs to the aspartokinase family. | 0.980 |
| hom-1 | serC | AMC85_CH01968 | AMC85_CH03617 | Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. | 0.537 |
| hom-1 | thrB | AMC85_CH01968 | AMC85_CH01032 | Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process. | Homoserine kinase; Protein involved in transferase activity, transferring phosphorus-containing groups; Belongs to the pseudomonas-type ThrB family. | 0.937 |
| hom-1 | thrC | AMC85_CH01968 | AMC85_CH01049 | Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process. | Protein involved in threonine synthase activity, pyridoxal phosphate binding and threonine biosynthetic process. | 0.967 |
| ilvA | ANL61044.1 | AMC85_CH01850 | AMC85_CH03710 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | 0.924 |
| ilvA | ANL61686.1 | AMC85_CH01850 | AMC85_CH04367 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | 0.925 |
| ilvA | ltaE | AMC85_CH01850 | AMC85_CH03743 | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | Low-specificity threonine aldolase; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.912 |
