| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL58508.1 | ANL58581.1 | AMC85_CH01090 | AMC85_CH01164 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | 0.820 |
| ANL58508.1 | dnaN | AMC85_CH01090 | AMC85_CH00356 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.783 |
| ANL58508.1 | holB | AMC85_CH01090 | AMC85_CH02239 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | DNA polymerase III delta' subunit. | 0.771 |
| ANL58508.1 | mutL | AMC85_CH01090 | AMC85_CH00916 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.816 |
| ANL58508.1 | mutS | AMC85_CH01090 | AMC85_CH00428 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | DNA mismatch repair protein MutS; This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity. | 0.799 |
| ANL58508.1 | polA | AMC85_CH01090 | AMC85_CH00194 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.943 |
| ANL58508.1 | rarA | AMC85_CH01090 | AMC85_CH01786 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | Recombination factor protein RarA; Protein involved in four-way junction helicase activity, nucleoside-triphosphatase activity, DNA repair and DNA recombination. | 0.807 |
| ANL58508.1 | recA | AMC85_CH01090 | AMC85_CH02417 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.876 |
| ANL58508.1 | rnhB | AMC85_CH01090 | AMC85_CH00936 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | Ribonuclease HII; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. | 0.807 |
| ANL58508.1 | topA | AMC85_CH01090 | AMC85_CH01707 | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.910 |
| ANL58581.1 | ANL58508.1 | AMC85_CH01164 | AMC85_CH01090 | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | 0.820 |
| ANL58581.1 | dnaN | AMC85_CH01164 | AMC85_CH00356 | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.474 |
| ANL58581.1 | holB | AMC85_CH01164 | AMC85_CH02239 | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | DNA polymerase III delta' subunit. | 0.655 |
| ANL58581.1 | mutL | AMC85_CH01164 | AMC85_CH00916 | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | DNA mismatch repair protein MutL; This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex. | 0.418 |
| ANL58581.1 | polA | AMC85_CH01164 | AMC85_CH00194 | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.966 |
| ANL58581.1 | recA | AMC85_CH01164 | AMC85_CH02417 | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | Recombinase A; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.629 |
| ANL58581.1 | topA | AMC85_CH01164 | AMC85_CH01707 | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | DNA topoisomerase 1; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.703 |
| dnaN | ANL58508.1 | AMC85_CH00356 | AMC85_CH01090 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DEAD/DEAH box type DNA/RNA helicase protein; Protein involved in nucleic acid binding, ATP binding, ATP-dependent helicase activity and DNA recombination. | 0.783 |
| dnaN | ANL58581.1 | AMC85_CH00356 | AMC85_CH01164 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction. | 0.474 |
| dnaN | holB | AMC85_CH00356 | AMC85_CH02239 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III delta' subunit. | 0.995 |
