Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL58793.1 | cusR | AMC85_CH01380 | AMC85_CH01379 | Sensor histidine kinase protein; Protein involved in signal transducer activity, protein histidine kinase activity, signal transduction and peptidyl-histidine phosphorylation. | Response regulator CusR; Protein involved in two-component response regulator activity, DNA binding, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent. | 0.966 |
| ANL58793.1 | glnE | AMC85_CH01380 | AMC85_CH01381 | Sensor histidine kinase protein; Protein involved in signal transducer activity, protein histidine kinase activity, signal transduction and peptidyl-histidine phosphorylation. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.533 |
| amtB | glnA | AMC85_CH04236 | AMC85_CH02173 | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | Glutamine synthetase; Protein involved in catalytic activity, glutamine biosynthetic process and nitrogen compound metabolic process. | 0.727 |
| amtB | glnD | AMC85_CH04236 | AMC85_CH00426 | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.788 |
| amtB | glnE | AMC85_CH04236 | AMC85_CH01381 | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.727 |
| amtB | gltB | AMC85_CH04236 | AMC85_CH03742 | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | Glutamate synthase (NADPH) large subunit; Protein involved in catalytic activity, oxidoreductase activity, acting on the CH-NH2 group of donors, nitrogen compound metabolic process and oxidation-reduction process. | 0.724 |
| amtB | nadE-2 | AMC85_CH04236 | AMC85_CH02457 | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | NAD(+) synthetase 2; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. | 0.495 |
| amtB | ntrB | AMC85_CH04236 | AMC85_CH02069 | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | Protein involved in signal transducer activity and regulation of transcription, DNA-dependent. | 0.862 |
| amtB | ntrC | AMC85_CH04236 | AMC85_CH02070 | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | Nitrogen assimilation regulatory protein NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.588 |
| bcp | glnE | AMC85_CH02367 | AMC85_CH01381 | Peroxiredoxin Bcp; Protein involved in antioxidant activity, oxidoreductase activity and oxidation-reduction process. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.648 |
| cusR | ANL58793.1 | AMC85_CH01379 | AMC85_CH01380 | Response regulator CusR; Protein involved in two-component response regulator activity, DNA binding, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent. | Sensor histidine kinase protein; Protein involved in signal transducer activity, protein histidine kinase activity, signal transduction and peptidyl-histidine phosphorylation. | 0.966 |
| cusR | glnE | AMC85_CH01379 | AMC85_CH01381 | Response regulator CusR; Protein involved in two-component response regulator activity, DNA binding, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.541 |
| glnA | amtB | AMC85_CH02173 | AMC85_CH04236 | Glutamine synthetase; Protein involved in catalytic activity, glutamine biosynthetic process and nitrogen compound metabolic process. | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | 0.727 |
| glnA | glnD | AMC85_CH02173 | AMC85_CH00426 | Glutamine synthetase; Protein involved in catalytic activity, glutamine biosynthetic process and nitrogen compound metabolic process. | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | 0.597 |
| glnA | glnE | AMC85_CH02173 | AMC85_CH01381 | Glutamine synthetase; Protein involved in catalytic activity, glutamine biosynthetic process and nitrogen compound metabolic process. | Glutamate-ammonia-ligase adenylyltransferase; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory region of GlnE binds the signal transd [...] | 0.721 |
| glnA | gltB | AMC85_CH02173 | AMC85_CH03742 | Glutamine synthetase; Protein involved in catalytic activity, glutamine biosynthetic process and nitrogen compound metabolic process. | Glutamate synthase (NADPH) large subunit; Protein involved in catalytic activity, oxidoreductase activity, acting on the CH-NH2 group of donors, nitrogen compound metabolic process and oxidation-reduction process. | 0.985 |
| glnA | ntrB | AMC85_CH02173 | AMC85_CH02069 | Glutamine synthetase; Protein involved in catalytic activity, glutamine biosynthetic process and nitrogen compound metabolic process. | Protein involved in signal transducer activity and regulation of transcription, DNA-dependent. | 0.489 |
| glnA | ntrC | AMC85_CH02173 | AMC85_CH02070 | Glutamine synthetase; Protein involved in catalytic activity, glutamine biosynthetic process and nitrogen compound metabolic process. | Nitrogen assimilation regulatory protein NtrC; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes. | 0.573 |
| glnD | amtB | AMC85_CH00426 | AMC85_CH04236 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport. | 0.788 |
| glnD | glnA | AMC85_CH00426 | AMC85_CH02173 | PII uridylyl-transferase; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen metabolism. | Glutamine synthetase; Protein involved in catalytic activity, glutamine biosynthetic process and nitrogen compound metabolic process. | 0.597 |
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