Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
amnAMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations. (500 aa)    
Predicted Functional Partners:
deoD
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
 0.912
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
   
 0.912
ade-1
Adenine deaminase 1; Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
  0.908
ade-2
Adenine deaminase 2; Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
    
  0.908
ANL61065.1
Protein involved in hydrolase activity and cell wall macromolecule catabolic process; Belongs to the 5'-nucleotidase family.
     
 0.902
ANL60521.1
Multicopper polyphenol oxidoreductase laccase domain-containig protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
 0.901
adk
Adenylate kinase; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family.
     
  0.900
surE-1
5'-nucleotidase SurE 1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
  0.900
mazG
Nucleoside triphosphate pyrophosphohydrolase.
     
  0.900
purB
Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
 
  0.900
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
Server load: low (34%) [HD]