STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANL58832.1Histidinol-phosphate aminotransferase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process. (370 aa)    
Predicted Functional Partners:
hisB
Protein involved in imidazoleglycerol-phosphate dehydratase activity and histidine biosynthetic process.
 
 0.994
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine.
  
 0.972
tyrC
Bifunctional cyclohexadienyl dehydrogenase/prephenate dehydrogenase; Protein involved in nucleotide binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and oxidation-reduction process.
  
 
 0.970
ANL57613.1
Protein involved in prephenate dehydratase activity and L-phenylalanine biosynthetic process.
  
 
 0.962
hisC-1
Histidinol-phosphate aminotransferase 1; Protein involved in catalytic activity, pyridoxal phosphate binding and histidine biosynthetic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
0.926
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF.
 
  
 0.919
dat
D-alanine aminotransferase; Protein involved in catalytic activity and metabolic process.
  
 
 0.915
hisC-2
Histidinol-phosphate aminotransferase 2; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
0.915
ANL59222.1
Protein involved in 4-hydroxyphenylpyruvate dioxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, aromatic amino acid family metabolic process and oxidation-reduction process.
    
 0.913
hisG
ATP phosphoribosyltransferase catalytic subunit; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.
 
  
 0.910
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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