Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
iolD3,5/4-trihydroxycyclohexane-1,2-dione hydrolase; Protein involved in thiamine pyrophosphate binding; Belongs to the TPP enzyme family. (616 aa)    
Predicted Functional Partners:
iolB
5-deoxy-glucuronate isomerase; Protein involved in intramolecular oxidoreductase activity, interconverting aldoses and ketoses and metabolic process.
 
 
 0.999
iolE-1
Myo-inosose-2 dehydratase 1.
 
 
 0.994
ANL58844.1
Sugar kinase IolC-like protein; Protein involved in phosphotransferase activity, alcohol group as acceptor.
 
  
 0.960
iolA
Methylmalonate-semialdehyde dehydrogenase (acylating); Protein involved in oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, metabolic process and oxidation-reduction process.
 
  
 0.894
idhA-1
Myo-inositol 2-dehydrogenase 1; Protein involved in nucleotide binding, metabolic process and oxidation-reduction process.
 
  
 0.837
ANL58846.1
Protein involved in nucleotide binding, metabolic process and oxidation-reduction process.
 
  
 0.835
ANL58845.1
RpiR family transcriptional regulator protein; Protein involved in sugar binding and carbohydrate metabolic process.
 
   
 0.822
ANL59199.1
Protein involved in nucleotide binding, metabolic process and oxidation-reduction process.
 
  
 0.743
ANL59548.1
Hemimethylated DNA-binding domain-containing protein; Protein involved in DNA binding.
      
 0.718
arcB
Arginase; Protein involved in arginase activity, metal ion binding and arginine metabolic process; Belongs to the arginase family.
      
 0.582
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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