STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
birAbiotin--(acetyl-CoA carboxylase) ligase; Protein involved in biotin-[acetyl-CoA-carboxylase] ligase activity and protein modification process. (254 aa)    
Predicted Functional Partners:
accC-1
acetyl-CoA carboxylase biotin carboxylase subunit AccC 1; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 0.955
accB-1
acetyl-CoA carboxylase biotin carboxyl carrier subunit AccB 1; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 
 0.941
ANL61022.1
acetyl/propionyl-CoA carboxylase alpha subunit protein; Protein involved in ATP binding, ligase activity and metabolic process.
 
  
 0.937
pccA
propionyl-CoA carboxylase subunit alpha; Protein involved in ATP binding, ligase activity and metabolic process.
 
  
 0.931
pyc
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
 
 
 0.891
pccB
propionyl-CoA carboxylase beta subunit; Protein involved in ligase activity.
 
 
 0.886
ANL59090.1
Protein involved in hydrolase activity.
      0.870
bioY
Biotin transporter protein BioY.
 
   
 0.862
nuoM-1
NADH dehydrogenase (quinone) subunit M 1; Protein involved in NADH dehydrogenase (ubiquinone) activity, ATP synthesis coupled electron transport and oxidation-reduction process.
  
  
 0.859
nuoN-1
NADH dehydrogenase (quinone) subunit N 1; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient; Belongs to the complex I subunit 2 family.
  
    0.820
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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