STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
phhAPhenylalanine 4-monooxygenase; Protein involved in oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen, iron ion binding and oxidation-reduction process. (263 aa)    
Predicted Functional Partners:
ANL61518.1
Protein involved in 4-alpha-hydroxytetrahydrobiopterin dehydratase activity and tetrahydrobiopterin biosynthetic process.
 
 0.991
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
 
  
 0.954
ANL59222.1
Protein involved in 4-hydroxyphenylpyruvate dioxygenase activity, oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, aromatic amino acid family metabolic process and oxidation-reduction process.
 
  
 0.919
tyrC
Bifunctional cyclohexadienyl dehydrogenase/prephenate dehydrogenase; Protein involved in nucleotide binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor and oxidation-reduction process.
     
 0.915
ANL57613.1
Protein involved in prephenate dehydratase activity and L-phenylalanine biosynthetic process.
     
 0.909
ANL58832.1
Histidinol-phosphate aminotransferase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process.
     
 0.908
hisC-1
Histidinol-phosphate aminotransferase 1; Protein involved in catalytic activity, pyridoxal phosphate binding and histidine biosynthetic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.908
hisC-2
Histidinol-phosphate aminotransferase 2; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
     
 0.908
aatA-1
Aspartate aminotransferase A 1; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process.
   
 
 0.907
folA
Dihydrofolate reductase; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis.
     
  0.900
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
Server load: medium (46%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.