node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANL59293.1 | surE-1 | AMC85_CH01905 | AMC85_CH01915 | Deoxyguanosinetriphosphate triphosphohydrolase-like protein; Protein involved in phosphoric diester hydrolase activity, metal ion binding and GTP metabolic process; Belongs to the dGTPase family. Type 2 subfamily. | 5'-nucleotidase SurE 1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.934 |
cmk | guaA | AMC85_CH00103 | AMC85_CH00335 | Protein involved in cytidylate kinase activity, ATP binding and nucleobase-containing compound metabolic process. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.618 |
cmk | guaB | AMC85_CH00103 | AMC85_CH00859 | Protein involved in cytidylate kinase activity, ATP binding and nucleobase-containing compound metabolic process. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.669 |
cmk | purH | AMC85_CH00103 | AMC85_CH04383 | Protein involved in cytidylate kinase activity, ATP binding and nucleobase-containing compound metabolic process. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Protein involved in catalytic activity. | 0.500 |
cmk | pyrF | AMC85_CH00103 | AMC85_CH00352 | Protein involved in cytidylate kinase activity, ATP binding and nucleobase-containing compound metabolic process. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.695 |
cmk | pyrH | AMC85_CH00103 | AMC85_CH02036 | Protein involved in cytidylate kinase activity, ATP binding and nucleobase-containing compound metabolic process. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.650 |
cmk | surE-1 | AMC85_CH00103 | AMC85_CH01915 | Protein involved in cytidylate kinase activity, ATP binding and nucleobase-containing compound metabolic process. | 5'-nucleotidase SurE 1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.925 |
deoA | guaA | AMC85_CH00241 | AMC85_CH00335 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.455 |
deoA | guaB | AMC85_CH00241 | AMC85_CH00859 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.470 |
deoA | surE-1 | AMC85_CH00241 | AMC85_CH01915 | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 5'-nucleotidase SurE 1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.934 |
guaA | cmk | AMC85_CH00335 | AMC85_CH00103 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Protein involved in cytidylate kinase activity, ATP binding and nucleobase-containing compound metabolic process. | 0.618 |
guaA | deoA | AMC85_CH00335 | AMC85_CH00241 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.455 |
guaA | guaB | AMC85_CH00335 | AMC85_CH00859 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.999 |
guaA | purB | AMC85_CH00335 | AMC85_CH02378 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Adenylosuccinate lyase; Protein involved in catalytic activity and purine ribonucleotide biosynthetic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.919 |
guaA | purH | AMC85_CH00335 | AMC85_CH04383 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; Protein involved in catalytic activity. | 0.931 |
guaA | pyrF | AMC85_CH00335 | AMC85_CH00352 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Orotidine 5'-phosphate decarboxylase; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. | 0.613 |
guaA | pyrH | AMC85_CH00335 | AMC85_CH02036 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.771 |
guaA | surE-1 | AMC85_CH00335 | AMC85_CH01915 | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 5'-nucleotidase SurE 1; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.948 |
guaB | cmk | AMC85_CH00859 | AMC85_CH00103 | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Protein involved in cytidylate kinase activity, ATP binding and nucleobase-containing compound metabolic process. | 0.669 |
guaB | deoA | AMC85_CH00859 | AMC85_CH00241 | Inosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. | 0.470 |