STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metCCystathionine beta-lyase; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process. (396 aa)    
Predicted Functional Partners:
cysK
Protein involved in cysteine synthase activity, pyridoxal phosphate binding and cysteine biosynthetic process from serine.
 
 0.988
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.981
cysB
Cysteine synthase; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process.
 
 0.980
sseA
3-mercaptopyruvate sulfurtransferase.
 
 
 0.952
ANL59046.1
O-acetylhomoserine aminocarboxypropyltransferase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and cellular amino acid metabolic process.
 
 
0.944
ahcY
S-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
  
 0.927
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
  
  
 
0.923
aatA-1
Aspartate aminotransferase A 1; Protein involved in catalytic activity, pyridoxal phosphate binding and biosynthetic process.
  
 
 0.919
hom-1
Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process.
  
 
 0.886
ilvA
Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA.
  
 
 0.826
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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