| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL57719.1 | gyrB-2 | AMC85_CH00282 | AMC85_CH02271 | GFA family glutathione-dependent formaldehyde-activating protein; Protein involved in carbon-sulfur lyase activity and metabolic process. | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.720 |
| ANL57808.1 | gyrB-2 | AMC85_CH00374 | AMC85_CH02271 | GFA family glutathione-dependent formaldehyde-activating protein; Protein involved in carbon-sulfur lyase activity and metabolic process. | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.720 |
| ANL58031.1 | gyrB-2 | AMC85_CH00605 | AMC85_CH02271 | GFA family glutathione-dependent formaldehyde-activating protein; Protein involved in carbon-sulfur lyase activity and metabolic process. | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.720 |
| cpaE | ctpA | AMC85_CH00254 | AMC85_CH04353 | Flp pilus assembly ATP-binding protein CpaE. | Carboxy-terminal processing protease; Protein involved in serine-type peptidase activity and proteolysis; Belongs to the peptidase S41A family. | 0.719 |
| cpaE | gyrB-2 | AMC85_CH00254 | AMC85_CH02271 | Flp pilus assembly ATP-binding protein CpaE. | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.746 |
| cpaE | tadA | AMC85_CH00254 | AMC85_CH00901 | Flp pilus assembly ATP-binding protein CpaE. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.741 |
| ctpA | cpaE | AMC85_CH04353 | AMC85_CH00254 | Carboxy-terminal processing protease; Protein involved in serine-type peptidase activity and proteolysis; Belongs to the peptidase S41A family. | Flp pilus assembly ATP-binding protein CpaE. | 0.719 |
| ctpA | gyrB-2 | AMC85_CH04353 | AMC85_CH02271 | Carboxy-terminal processing protease; Protein involved in serine-type peptidase activity and proteolysis; Belongs to the peptidase S41A family. | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.766 |
| ctpA | tadA | AMC85_CH04353 | AMC85_CH00901 | Carboxy-terminal processing protease; Protein involved in serine-type peptidase activity and proteolysis; Belongs to the peptidase S41A family. | tRNA-specific adenosine deaminase; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family. | 0.752 |
| dnaN | gyrA | AMC85_CH00356 | AMC85_CH02182 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.688 |
| dnaN | gyrB-2 | AMC85_CH00356 | AMC85_CH02271 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.747 |
| dnaN | parC | AMC85_CH00356 | AMC85_CH01560 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.577 |
| gyrA | dnaN | AMC85_CH02182 | AMC85_CH00356 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.688 |
| gyrA | gyrB-2 | AMC85_CH02182 | AMC85_CH02271 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | 0.992 |
| gyrA | parC | AMC85_CH02182 | AMC85_CH01560 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | DNA topoisomerase IV subunit A; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase GyrA/ParC subunit family. ParC type 1 subfamily. | 0.661 |
| gyrA | truB | AMC85_CH02182 | AMC85_CH00152 | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | tRNA pseudouridine(55) synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.403 |
| gyrB-2 | ANL57719.1 | AMC85_CH02271 | AMC85_CH00282 | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | GFA family glutathione-dependent formaldehyde-activating protein; Protein involved in carbon-sulfur lyase activity and metabolic process. | 0.720 |
| gyrB-2 | ANL57808.1 | AMC85_CH02271 | AMC85_CH00374 | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | GFA family glutathione-dependent formaldehyde-activating protein; Protein involved in carbon-sulfur lyase activity and metabolic process. | 0.720 |
| gyrB-2 | ANL58031.1 | AMC85_CH02271 | AMC85_CH00605 | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | GFA family glutathione-dependent formaldehyde-activating protein; Protein involved in carbon-sulfur lyase activity and metabolic process. | 0.720 |
| gyrB-2 | cpaE | AMC85_CH02271 | AMC85_CH00254 | DNA gyrase subunit B 2; Topoisomerase IV is essential for chromosome segregation. It relaxes supercoiled DNA. Performs the decatenation events required during the replication of a circular DNA molecule; Belongs to the type II topoisomerase family. ParE type 1 subfamily. | Flp pilus assembly ATP-binding protein CpaE. | 0.746 |
