| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL60274.1 | ANL61044.1 | AMC85_CH02913 | AMC85_CH03710 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | 0.910 |
| ANL60274.1 | ANL61686.1 | AMC85_CH02913 | AMC85_CH04367 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | 0.910 |
| ANL60274.1 | cysE-1 | AMC85_CH02913 | AMC85_CH01998 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Serine O-acetyltransferase 1; Protein involved in transferase activity and cysteine biosynthetic process from serine. | 0.842 |
| ANL60274.1 | cysE-2 | AMC85_CH02913 | AMC85_CH03809 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Serine O-acetyltransferase 2; Protein involved in transferase activity and cysteine biosynthetic process from serine. | 0.842 |
| ANL60274.1 | glyA-1 | AMC85_CH02913 | AMC85_CH01571 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
| ANL60274.1 | glyA-2 | AMC85_CH02913 | AMC85_CH02084 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.928 |
| ANL60274.1 | ilvA | AMC85_CH02913 | AMC85_CH01850 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.910 |
| ANL60274.1 | sdaA | AMC85_CH02913 | AMC85_CH02297 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Protein involved in L-serine ammonia-lyase activity, 4 iron, 4 sulfur cluster binding and gluconeogenesis; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.920 |
| ANL60274.1 | trpA | AMC85_CH02913 | AMC85_CH00022 | Protein involved in phosphoserine phosphatase activity and metabolic process. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.904 |
| ANL61044.1 | ANL60274.1 | AMC85_CH03710 | AMC85_CH02913 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Protein involved in phosphoserine phosphatase activity and metabolic process. | 0.910 |
| ANL61044.1 | ANL61686.1 | AMC85_CH03710 | AMC85_CH04367 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | 0.943 |
| ANL61044.1 | cysE-1 | AMC85_CH03710 | AMC85_CH01998 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Serine O-acetyltransferase 1; Protein involved in transferase activity and cysteine biosynthetic process from serine. | 0.804 |
| ANL61044.1 | cysE-2 | AMC85_CH03710 | AMC85_CH03809 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Serine O-acetyltransferase 2; Protein involved in transferase activity and cysteine biosynthetic process from serine. | 0.804 |
| ANL61044.1 | dsdA | AMC85_CH03710 | AMC85_CH02078 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | D-serine dehydratase; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process; Belongs to the serine/threonine dehydratase family. DsdA subfamily. | 0.904 |
| ANL61044.1 | glyA-1 | AMC85_CH03710 | AMC85_CH01571 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.906 |
| ANL61044.1 | glyA-2 | AMC85_CH03710 | AMC85_CH02084 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.906 |
| ANL61044.1 | ilvA | AMC85_CH03710 | AMC85_CH01850 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.924 |
| ANL61044.1 | sdaA | AMC85_CH03710 | AMC85_CH02297 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Protein involved in L-serine ammonia-lyase activity, 4 iron, 4 sulfur cluster binding and gluconeogenesis; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.920 |
| ANL61044.1 | trpA | AMC85_CH03710 | AMC85_CH00022 | Pyridoxal phosphate-dependent threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.918 |
| ANL61686.1 | ANL60274.1 | AMC85_CH04367 | AMC85_CH02913 | Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process. | Protein involved in phosphoserine phosphatase activity and metabolic process. | 0.910 |