STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pccApropionyl-CoA carboxylase subunit alpha; Protein involved in ATP binding, ligase activity and metabolic process. (669 aa)    
Predicted Functional Partners:
pccB
propionyl-CoA carboxylase beta subunit; Protein involved in ligase activity.
 0.999
accB-1
acetyl-CoA carboxylase biotin carboxyl carrier subunit AccB 1; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 
 
 0.974
ANL61279.1
AMP-dependent synthetase/ligase protein; Protein involved in catalytic activity and metabolic process.
 
 0.949
acsA
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.941
birA
biotin--(acetyl-CoA carboxylase) ligase; Protein involved in biotin-[acetyl-CoA-carboxylase] ligase activity and protein modification process.
 
  
 0.931
ANL59091.1
methylmalonyl-CoA epimerase protein.
 
 
 0.929
accD
acetyl-CoA carboxylase subunit beta; Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl-CoA.
 
 0.918
ANL61710.1
propionyl-CoA ligase protein; Protein involved in catalytic activity and metabolic process.
  
 0.914
ANL61022.1
acetyl/propionyl-CoA carboxylase alpha subunit protein; Protein involved in ATP binding, ligase activity and metabolic process.
  
  
 
0.911
iolA
Methylmalonate-semialdehyde dehydrogenase (acylating); Protein involved in oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, metabolic process and oxidation-reduction process.
   
 
 0.905
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.