Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of proteins in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL61464.1 | gcvH | AMC85_CH04142 | AMC85_CH02347 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Glycine-cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.984 |
| ANL61464.1 | gcvP | AMC85_CH04142 | AMC85_CH02348 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.955 |
| ANL61464.1 | gcvT | AMC85_CH04142 | AMC85_CH02346 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Protein involved in aminomethyltransferase activity and glycine catabolic process. | 0.952 |
| ANL61464.1 | glyA-1 | AMC85_CH04142 | AMC85_CH01571 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.916 |
| ANL61464.1 | glyA-2 | AMC85_CH04142 | AMC85_CH02084 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.916 |
| ANL61464.1 | lpdA | AMC85_CH04142 | AMC85_CH02061 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Dihydrolipoamide dehydrogenase; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | 0.912 |
| fhs | folD-1 | AMC85_CH03226 | AMC85_CH00743 | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 1; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.997 |
| fhs | folD-2 | AMC85_CH03226 | AMC85_CH02085 | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 2; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.997 |
| fhs | gcvH | AMC85_CH03226 | AMC85_CH02347 | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | Glycine-cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.491 |
| fhs | gcvP | AMC85_CH03226 | AMC85_CH02348 | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.714 |
| fhs | gcvT | AMC85_CH03226 | AMC85_CH02346 | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | Protein involved in aminomethyltransferase activity and glycine catabolic process. | 0.934 |
| fhs | glyA-1 | AMC85_CH03226 | AMC85_CH01571 | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.957 |
| fhs | glyA-2 | AMC85_CH03226 | AMC85_CH02084 | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.957 |
| fhs | metH | AMC85_CH03226 | AMC85_CH03036 | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.951 |
| folD-1 | fhs | AMC85_CH00743 | AMC85_CH03226 | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 1; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Protein involved in formate-tetrahydrofolate ligase activity, ATP binding and folic acid-containing compound biosynthetic process; Belongs to the formate--tetrahydrofolate ligase family. | 0.997 |
| folD-1 | folD-2 | AMC85_CH00743 | AMC85_CH02085 | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 1; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 2; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | 0.906 |
| folD-1 | gcvH | AMC85_CH00743 | AMC85_CH02347 | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 1; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Glycine-cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.436 |
| folD-1 | gcvP | AMC85_CH00743 | AMC85_CH02348 | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 1; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.695 |
| folD-1 | gcvT | AMC85_CH00743 | AMC85_CH02346 | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 1; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Protein involved in aminomethyltransferase activity and glycine catabolic process. | 0.948 |
| folD-1 | glyA-1 | AMC85_CH00743 | AMC85_CH01571 | Bifunctional 5,10-methylenetetrahydrofolate dehydrogenase/cyclohydrolase FolD 1; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.972 |
page 1 of 5