node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ANL57537.1 | ANL61464.1 | AMC85_CH00093 | AMC85_CH04142 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | 0.523 |
ANL57537.1 | gcvH | AMC85_CH00093 | AMC85_CH02347 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Glycine-cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.990 |
ANL57537.1 | gcvP | AMC85_CH00093 | AMC85_CH02348 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.976 |
ANL57537.1 | gcvT | AMC85_CH00093 | AMC85_CH02346 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Protein involved in aminomethyltransferase activity and glycine catabolic process. | 0.447 |
ANL57537.1 | glyA-1 | AMC85_CH00093 | AMC85_CH01571 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.630 |
ANL57537.1 | glyA-2 | AMC85_CH00093 | AMC85_CH02084 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.630 |
ANL57537.1 | lpdA | AMC85_CH00093 | AMC85_CH02061 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Dihydrolipoamide dehydrogenase; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | 0.523 |
ANL57537.1 | pdhB | AMC85_CH00093 | AMC85_CH02056 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.890 |
ANL57537.1 | soxA-1 | AMC85_CH00093 | AMC85_CH03782 | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | Sarcosine oxidase alpha subunit SoxA 1; Protein involved in nucleotide binding and oxidation-reduction process. | 0.956 |
ANL61464.1 | ANL57537.1 | AMC85_CH04142 | AMC85_CH00093 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | 0.523 |
ANL61464.1 | gcvH | AMC85_CH04142 | AMC85_CH02347 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Glycine-cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.984 |
ANL61464.1 | gcvP | AMC85_CH04142 | AMC85_CH02348 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.955 |
ANL61464.1 | gcvT | AMC85_CH04142 | AMC85_CH02346 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Protein involved in aminomethyltransferase activity and glycine catabolic process. | 0.952 |
ANL61464.1 | glyA-1 | AMC85_CH04142 | AMC85_CH01571 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.916 |
ANL61464.1 | glyA-2 | AMC85_CH04142 | AMC85_CH02084 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.916 |
ANL61464.1 | lipA | AMC85_CH04142 | AMC85_CH02064 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Lipoyl synthase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.498 |
ANL61464.1 | lpdA | AMC85_CH04142 | AMC85_CH02061 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Dihydrolipoamide dehydrogenase; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | 0.912 |
ANL61464.1 | pdhB | AMC85_CH04142 | AMC85_CH02056 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Pyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. | 0.999 |
ANL61464.1 | soxA-1 | AMC85_CH04142 | AMC85_CH03782 | Dihydrolipoamide dehydrogenase protein; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process. | Sarcosine oxidase alpha subunit SoxA 1; Protein involved in nucleotide binding and oxidation-reduction process. | 0.669 |
gcvH | ANL57537.1 | AMC85_CH02347 | AMC85_CH00093 | Glycine-cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | Sarcosine dehydrogenase protein; Protein involved in aminomethyltransferase activity and glycine catabolic process; Belongs to the GcvT family. | 0.990 |