STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ANL60179.1Fumarylacetoacetate hydrolase protein; Protein involved in catalytic activity and metabolic process. (231 aa)    
Predicted Functional Partners:
maiA-2
Maleylacetoacetate isomerase 2; Protein involved in catalytic activity and aromatic amino acid family metabolic process.
  
 
 0.926
fumC
Fumarate hydratase class 2; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.830
sdhA
Succinate dehydrogenase flavoprotein subunit; Protein involved in oxidoreductase activity, flavin adenine dinucleotide binding and oxidation-reduction process; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
  0.824
sdhB
Succinate dehydrogenase iron-sulfur subunit; Protein involved in electron carrier activity, iron-sulfur cluster binding and oxidation-reduction process; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
  0.812
fumA
Fumarate hydratase class 1; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
    
  0.804
sdhD
Protein involved in succinate dehydrogenase activity, heme binding and tricarboxylic acid cycle.
   
 
  0.804
sdhC
Succinate dehydrogenase cytochrome b556 subunit; Protein involved in succinate dehydrogenase activity and tricarboxylic acid cycle.
   
 
  0.803
ANL60180.1
Carbonic anhydrase/acetyltransferase family protein; Protein involved in transferase activity.
  
    0.770
hmgA
Homogentisate 1,2-dioxygenase; Involved in the catabolism of homogentisate (2,5- dihydroxyphenylacetate or 2,5-OH-PhAc), a central intermediate in the degradation of phenylalanine and tyrosine. Catalyzes the oxidative ring cleavage of the aromatic ring of homogentisate to yield maleylacetoacetate.
  
  
 0.711
dme
Malic enzyme; Protein involved in nucleotide binding, NAD binding and oxidation-reduction process.
 
 
 0.441
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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