STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dctAC4-dicarboxylate transport protein DctA; Responsible for the transport of dicarboxylates such as succinate, fumarate, and malate across the membrane. Belongs to the dicarboxylate/amino acid:cation symporter (DAACS) (TC 2.A.23) family. (444 aa)    
Predicted Functional Partners:
dctB
C4-dicarboxylate transport sensor histidine kinase DctB; Member of the two-component regulatory system DctB/DctD involved in the transport of C4-dicarboxylates. DctB functions as a membrane-associated protein kinase that phosphorylates DctD in response to environmental signals.
 
   
 0.897
dctD
C4-dicarboxylate transport response regulator DctD; Protein involved in protein binding, nucleoside-triphosphatase activity and regulation of transcription, DNA-dependent.
 
   
 0.835
dme
Malic enzyme; Protein involved in nucleotide binding, NAD binding and oxidation-reduction process.
  
  
 0.754
sdhD
Protein involved in succinate dehydrogenase activity, heme binding and tricarboxylic acid cycle.
   
  
 0.735
tme
NADP-dependent malic enzyme; Protein involved in nucleotide binding, NAD binding and oxidation-reduction process.
  
  
 0.706
ANL58035.1
Sensor histidine kinase/response regulator hybrid protein; Protein involved in signal transducer activity, protein histidine kinase activity, signal transduction and peptidyl-histidine phosphorylation.
  
  
 0.653
pckA
Phosphoenolpyruvate carboxykinase (ATP); Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.
  
  
 0.641
amtB
Protein involved in ammonium transmembrane transporter activity and ammonium transmembrane transport.
  
   
 0.600
gltA
Citrate synthase; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer and cellular carbohydrate metabolic process; Belongs to the citrate synthase family.
  
  
 0.550
flgF
Flagellar basal body rod protein FlgF; Protein involved in motor activity, structural molecule activity, cellular component movement and flagellum organization; Belongs to the flagella basal body rod proteins family.
    
   0.517
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.