Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANL60663.1Dihydroxy-acid/6-phosphogluconate dehydratase protein; Protein involved in catalytic activity and metabolic process; Belongs to the IlvD/Edd family. (579 aa)    
Predicted Functional Partners:
ilvC
Ketol-acid reductoisomerase; Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate.
 
 
 0.892
ilvI
Acetolactate synthase 3 large subunit; Protein involved in magnesium ion binding, acetolactate synthase activity, thiamine pyrophosphate binding, flavin adenine dinucleotide binding and branched chain family amino acid biosynthetic process.
 
 0.844
ANL57617.1
Carbohydrate/purine kinase protein; Protein involved in phosphotransferase activity, alcohol group as acceptor.
     
 0.800
ANL59789.1
Carbohydrate/purine kinase protein; Protein involved in hydrolase activity, acting on glycosyl bonds.
     
 0.800
ANL60890.1
Carbohydrate/purine kinase protein; Protein involved in phosphotransferase activity, alcohol group as acceptor.
     
 0.800
ilvH
Acetolactate synthase 3 small subunit; Protein involved in acetolactate synthase activity and branched chain family amino acid biosynthetic process.
 
 
 0.790
leuC
3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate.
 
  
 0.790
ANL58689.1
Aminotransferase class 4 protein; Protein involved in catalytic activity and metabolic process.
  
 0.766
ilvE
Protein involved in branched-chain-amino-acid transaminase activity and branched chain family amino acid metabolic process.
  
 0.766
ANL60364.1
Protein involved in thiamine pyrophosphate binding; Belongs to the TPP enzyme family.
 
 
 0.763
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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