Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ampCBeta-lactamase. (384 aa)    
Predicted Functional Partners:
ampR
LysR family transcriptional activator AmpR; Protein involved in sequence-specific DNA binding transcription factor activity and regulation of transcription, DNA-dependent; Belongs to the LysR transcriptional regulatory family.
 
   
 0.891
sugE
Quaternary ammonium compound-resistance protein SugE.
   
  
 0.818
ANL60346.1
Protein involved in N-acetylmuramoyl-L-alanine amidase activity and peptidoglycan catabolic process.
  
   
 0.790
mnmA
tRNA-specific 2-thiouridylase MnmA; Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.
     
 0.744
moaE
Molybdopterin synthase catalytic subunit; Protein involved in Mo-molybdopterin cofactor biosynthetic process.
      
 0.730
murB
UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation.
     
 0.659
nagZ
beta-N-acetylhexosaminidase; Protein involved in hydrolase activity, hydrolyzing O-glycosyl compounds and carbohydrate metabolic process.
 
  
 0.587
murI
Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis.
      
 0.528
sdaA
Protein involved in L-serine ammonia-lyase activity, 4 iron, 4 sulfur cluster binding and gluconeogenesis; Belongs to the iron-sulfur dependent L-serine dehydratase family.
      
 0.476
gyrB-1
DNA gyrase subunit B 1; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.461
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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