Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ade-2Adenine deaminase 2; Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family. (595 aa)    
Predicted Functional Partners:
xdhA
Xanthine dehydrogenase small subunit XdhA; Protein involved in UDP-N-acetylmuramate dehydrogenase activity, flavin adenine dinucleotide binding and oxidation-reduction process.
 
  
  0.921
ade-1
Adenine deaminase 1; Protein involved in hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds; Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.
  
  
 
0.920
xdhB
Xanthine dehydrogenase molybdopterin binding subunit XdhB; Protein involved in molybdenum ion binding and oxidation-reduction process.
 
  
  0.920
hpt
Protein involved in hypoxanthine phosphoribosyltransferase activity and purine ribonucleoside salvage; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
  0.919
amn
AMP nucleosidase; Catalyzes the hydrolysis of the N-glycosidic bond of AMP to form adenine and ribose 5-phosphate. Involved in regulation of AMP concentrations.
    
  0.908
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
    
 0.907
deoD
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
    
  0.901
ANL60521.1
Multicopper polyphenol oxidoreductase laccase domain-containig protein; Belongs to the multicopper oxidase YfiH/RL5 family.
    
  0.900
ANL60924.1
Inosine/uridine preferring nucleoside hydrolase protein.
 
     0.863
ANL60922.1
Spermidine/putrescine ABC transporter permease protein; Protein involved in transporter activity and transport.
 
     0.853
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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