Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANL60980.1Toxin-antitoxin system PIN domain-containing protein. (137 aa)    
Predicted Functional Partners:
vapB
Toxin-antitoxin system antitoxin protein VapB.
 
 
 0.806
ruvA
Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
       0.793
ANL60979.1
AbrB/SpoV domain-containing protein.
       0.786
ruvC
Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.
       0.663
ruvB
Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
       0.605
ANL60983.1
Metallophosphoesterase domain-containing protein; Protein involved in hydrolase activity.
       0.555
ANL60984.1
Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family.
       0.550
ANL58644.1
Type II toxin-antitoxin system antitoxin Phd/YefM family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
   
 0.493
ANL58317.1
Type II toxin-antitoxin system antitoxin Phd/YefM family protein; Antitoxin component of a type II toxin-antitoxin (TA) system.
 
   
 0.465
ANL60985.1
DinB family DNA damage-inducible protein.
       0.450
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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