| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL60983.1 | ANL60984.1 | AMC85_CH03646 | AMC85_CH03647 | Metallophosphoesterase domain-containing protein; Protein involved in hydrolase activity. | Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. | 0.791 |
| ANL60983.1 | ANL60985.1 | AMC85_CH03646 | AMC85_CH03648 | Metallophosphoesterase domain-containing protein; Protein involved in hydrolase activity. | DinB family DNA damage-inducible protein. | 0.661 |
| ANL60983.1 | ruvA | AMC85_CH03646 | AMC85_CH03644 | Metallophosphoesterase domain-containing protein; Protein involved in hydrolase activity. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.590 |
| ANL60983.1 | ruvB | AMC85_CH03646 | AMC85_CH03645 | Metallophosphoesterase domain-containing protein; Protein involved in hydrolase activity. | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.794 |
| ANL60983.1 | ruvC | AMC85_CH03646 | AMC85_CH03641 | Metallophosphoesterase domain-containing protein; Protein involved in hydrolase activity. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.466 |
| ANL60984.1 | ANL60983.1 | AMC85_CH03647 | AMC85_CH03646 | Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. | Metallophosphoesterase domain-containing protein; Protein involved in hydrolase activity. | 0.791 |
| ANL60984.1 | ANL60985.1 | AMC85_CH03647 | AMC85_CH03648 | Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. | DinB family DNA damage-inducible protein. | 0.672 |
| ANL60984.1 | ruvA | AMC85_CH03647 | AMC85_CH03644 | Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.599 |
| ANL60984.1 | ruvB | AMC85_CH03647 | AMC85_CH03645 | Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.801 |
| ANL60984.1 | ruvC | AMC85_CH03647 | AMC85_CH03641 | Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.475 |
| ANL60985.1 | ANL60983.1 | AMC85_CH03648 | AMC85_CH03646 | DinB family DNA damage-inducible protein. | Metallophosphoesterase domain-containing protein; Protein involved in hydrolase activity. | 0.661 |
| ANL60985.1 | ANL60984.1 | AMC85_CH03648 | AMC85_CH03647 | DinB family DNA damage-inducible protein. | Protein involved in hydrolase activity; Belongs to the Nudix hydrolase family. | 0.672 |
| ANL60985.1 | ruvA | AMC85_CH03648 | AMC85_CH03644 | DinB family DNA damage-inducible protein. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.495 |
| ANL60985.1 | ruvB | AMC85_CH03648 | AMC85_CH03645 | DinB family DNA damage-inducible protein. | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.672 |
| ligA | mfd | AMC85_CH02961 | AMC85_CH02166 | DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | Transcription-repair coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.512 |
| ligA | polA | AMC85_CH02961 | AMC85_CH00194 | DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.727 |
| ligA | rpoC | AMC85_CH02961 | AMC85_CH01742 | DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.546 |
| ligA | ruvA | AMC85_CH02961 | AMC85_CH03644 | DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | Holliday junction ATP-dependent DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.581 |
| ligA | ruvB | AMC85_CH02961 | AMC85_CH03645 | DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | Holliday junction ATP-dependent DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.687 |
| ligA | ruvC | AMC85_CH02961 | AMC85_CH03641 | DNA ligase (NAD(+)); DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA; Belongs to the NAD-dependent DNA ligase family. LigA subfamily. | Crossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. | 0.547 |