Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANL61135.1D-2-hydroxyacid dehydrogenase protein; Protein involved in nucleotide binding, cofactor binding and oxidation-reduction process; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (318 aa)    
Predicted Functional Partners:
ANL61136.1
LacI family transcriptional regulator protein; Protein involved in DNA binding and regulation of transcription, DNA-dependent.
  
    0.707
pgm
Phosphoglucomutase; Protein involved in intramolecular transferase activity, phosphotransferases and carbohydrate metabolic process.
  
   0.513
ANL61137.1
MarR family transcriptional regulator protein; Protein involved in sequence-specific DNA binding transcription factor activity and regulation of transcription, DNA-dependent.
       0.490
tme
NADP-dependent malic enzyme; Protein involved in nucleotide binding, NAD binding and oxidation-reduction process.
   
 
 0.476
dme
Malic enzyme; Protein involved in nucleotide binding, NAD binding and oxidation-reduction process.
   
 
 0.476
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
  
 0.463
nnrE
Carbohydrate kinase-related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the rep [...]
  
   0.441
uppS
Undecaprenyl pyrophosphate synthase; Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.
  
     0.420
tal
Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.
  
  
 0.413
ANL61138.1
Creatininase protein.
       0.405
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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