Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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Score
cysE-2Serine O-acetyltransferase 2; Protein involved in transferase activity and cysteine biosynthetic process from serine. (272 aa)    
Predicted Functional Partners:
cysK
Protein involved in cysteine synthase activity, pyridoxal phosphate binding and cysteine biosynthetic process from serine.
 
 0.993
cysB
Cysteine synthase; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process.
 
 0.982
sdaA
Protein involved in L-serine ammonia-lyase activity, 4 iron, 4 sulfur cluster binding and gluconeogenesis; Belongs to the iron-sulfur dependent L-serine dehydratase family.
     
 0.915
cysE-1
Serine O-acetyltransferase 1; Protein involved in transferase activity and cysteine biosynthetic process from serine.
  
  
0.913
cysS
cysteinyl-tRNA synthetase; Protein involved in cysteine-tRNA ligase activity, ATP binding and cysteinyl-tRNA aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.910
ANL61686.1
Pyridoxal phosphate-dependent serine/threonine dehydratase protein; Protein involved in catalytic activity, pyridoxal phosphate binding and metabolic process.
    
 0.905
ANL60274.1
Protein involved in phosphoserine phosphatase activity and metabolic process.
    
 0.839
hom-1
Protein involved in homoserine dehydrogenase activity, NADP binding, cellular amino acid metabolic process and oxidation-reduction process.
     
 0.826
glyA-1
Serine hydroxymethyltransferase 1; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.820
glyA-2
Serine hydroxymethyltransferase 2; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.820
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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