Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Score
ANL61329.1Protein involved in heat shock protein binding, unfolded protein binding and protein folding. (205 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 0.950
grpE
Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...]
  
 
 0.945
ANL58802.1
HSP70 family molecular chaperone protein; Protein involved in ATP binding.
 
 0.940
ANL58581.1
Adenylate cyclase family 3 protein; Protein involved in binding, cyclic nucleotide biosynthetic process and intracellular signal transduction.
   
 0.776
ANL61140.1
WD40/YVTN repeat-like domain-containing protein; Protein involved in protein binding.
 
 
 0.771
rplQ
50S ribosomal protein L17; Protein involved in structural constituent of ribosome and translation.
  
 
 0.768
rpoC
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 
 0.762
groEL-1
Chaperonin GroEL 1; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.761
groEL-2
Chaperonin GroEL 2; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
  
 0.761
ANL59981.1
MIP family aquaporin-like protein; Protein involved in transporter activity and transport; Belongs to the MIP/aquaporin (TC 1.A.8) family.
    
 
 0.752
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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