Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ANL61353.1Protein involved in asparagine synthase (glutamine-hydrolyzing) activity and asparagine biosynthetic process. (513 aa)    
Predicted Functional Partners:
ANL61352.1
Protein involved in amino acid transport.
       0.773
ANL61354.1
Protein involved in methyltransferase activity and metabolic process.
  
    0.754
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).
   
 
 0.606
gltB
Glutamate synthase (NADPH) large subunit; Protein involved in catalytic activity, oxidoreductase activity, acting on the CH-NH2 group of donors, nitrogen compound metabolic process and oxidation-reduction process.
  
  
 0.598
metH
B12-dependent methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
 
  
 0.561
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.
   
 
 0.541
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
  
  
 0.478
ANL60987.1
Lysylphosphatidylglycerol synthetase domain-containing protein.
     
 0.473
lysC
Protein involved in aspartate kinase activity and lysine biosynthetic process via diaminopimelate; Belongs to the aspartokinase family.
  
  
 0.461
ppnK
NAD(+) kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 
 0.411
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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