imuA protein (Rhizobium phaseoli) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

imuA

Inducible mutagenesis protein ImuA. (251 aa)

Predicted Functional Partners:

imuB-2

0.993

dnaE2-1

0.984

imuB-1

0.977

dnaE2-2

0.946

dinB-1

0.915

dnaE1

0.819

ANL60432.1

0.580

ANL61356.1

0.572

lexA

0.516

ANL61367.1

0.416

Your Current Organism:

Rhizobium phaseoli

NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc.

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ANL60432.1	imuA	AMC85_CH03078	AMC85_CH04044	SOS response-associated peptidase protein.	Inducible mutagenesis protein ImuA.	0.580
ANL61356.1	imuA	AMC85_CH04034	AMC85_CH04044	SOS response-associated peptidase protein.	Inducible mutagenesis protein ImuA.	0.572
ANL61367.1	imuA	AMC85_CH04045	AMC85_CH04044	Hypothetical protein.	Inducible mutagenesis protein ImuA.	0.416
dinB-1	dnaE1	AMC85_CH01696	AMC85_CH01694	DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	DNA polymerase III subunit alpha; Protein involved in catalytic activity, DNA-directed DNA polymerase activity and DNA replication.	0.489
dinB-1	dnaE2-1	AMC85_CH01696	AMC85_CH04042	DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	Error-prone DNA polymerase 1; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	0.830
dinB-1	dnaE2-2	AMC85_CH01696	AMC85_CH04358	DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	Error-prone DNA polymerase 2; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	0.830
dinB-1	imuA	AMC85_CH01696	AMC85_CH04044	DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	Inducible mutagenesis protein ImuA.	0.915
dinB-1	lexA	AMC85_CH01696	AMC85_CH02049	DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.938
dnaE1	dinB-1	AMC85_CH01694	AMC85_CH01696	DNA polymerase III subunit alpha; Protein involved in catalytic activity, DNA-directed DNA polymerase activity and DNA replication.	DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	0.489
dnaE1	imuA	AMC85_CH01694	AMC85_CH04044	DNA polymerase III subunit alpha; Protein involved in catalytic activity, DNA-directed DNA polymerase activity and DNA replication.	Inducible mutagenesis protein ImuA.	0.819
dnaE1	imuB-1	AMC85_CH01694	AMC85_CH04359	DNA polymerase III subunit alpha; Protein involved in catalytic activity, DNA-directed DNA polymerase activity and DNA replication.	DNA-repair protein ImuB 1; Protein involved in damaged DNA binding, DNA-directed DNA polymerase activity and DNA repair.	0.883
dnaE1	imuB-2	AMC85_CH01694	AMC85_CH04043	DNA polymerase III subunit alpha; Protein involved in catalytic activity, DNA-directed DNA polymerase activity and DNA replication.	DNA-repair protein ImuB 2.	0.868
dnaE1	lexA	AMC85_CH01694	AMC85_CH02049	DNA polymerase III subunit alpha; Protein involved in catalytic activity, DNA-directed DNA polymerase activity and DNA replication.	Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.431
dnaE2-1	dinB-1	AMC85_CH04042	AMC85_CH01696	Error-prone DNA polymerase 1; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	0.830
dnaE2-1	imuA	AMC85_CH04042	AMC85_CH04044	Error-prone DNA polymerase 1; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	Inducible mutagenesis protein ImuA.	0.984
dnaE2-1	imuB-1	AMC85_CH04042	AMC85_CH04359	Error-prone DNA polymerase 1; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	DNA-repair protein ImuB 1; Protein involved in damaged DNA binding, DNA-directed DNA polymerase activity and DNA repair.	0.961
dnaE2-1	imuB-2	AMC85_CH04042	AMC85_CH04043	Error-prone DNA polymerase 1; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	DNA-repair protein ImuB 2.	0.984
dnaE2-1	lexA	AMC85_CH04042	AMC85_CH02049	Error-prone DNA polymerase 1; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	Repressor LexA; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.	0.547
dnaE2-2	dinB-1	AMC85_CH04358	AMC85_CH01696	Error-prone DNA polymerase 2; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	DNA polymerase IV 1; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.	0.830
dnaE2-2	imuA	AMC85_CH04358	AMC85_CH04044	Error-prone DNA polymerase 2; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase.	Inducible mutagenesis protein ImuA.	0.946