| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ANL58097.1 | rpoB | AMC85_CH00673 | AMC85_CH01741 | Protein involved in two-component response regulator activity, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.512 |
| ANL58097.1 | sodB | AMC85_CH00673 | AMC85_CH01287 | Protein involved in two-component response regulator activity, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.446 |
| ANL58097.1 | soxR | AMC85_CH00673 | AMC85_CH04121 | Protein involved in two-component response regulator activity, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent. | Redox-sensitive transcriptional activator SoxR; Protein involved in DNA binding, sequence-specific DNA binding transcription factor activity, iron ion binding, regulation of transcription, DNA-dependent and response to oxidative stress. | 0.442 |
| ANL58429.1 | grpE | AMC85_CH01010 | AMC85_CH00403 | DnaJ family heat shock protein; Protein involved in unfolded protein binding and protein folding. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.950 |
| ANL58429.1 | sodB | AMC85_CH01010 | AMC85_CH01287 | DnaJ family heat shock protein; Protein involved in unfolded protein binding and protein folding. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.884 |
| ANL58429.1 | soxR | AMC85_CH01010 | AMC85_CH04121 | DnaJ family heat shock protein; Protein involved in unfolded protein binding and protein folding. | Redox-sensitive transcriptional activator SoxR; Protein involved in DNA binding, sequence-specific DNA binding transcription factor activity, iron ion binding, regulation of transcription, DNA-dependent and response to oxidative stress. | 0.499 |
| ANL61329.1 | grpE | AMC85_CH04007 | AMC85_CH00403 | Protein involved in heat shock protein binding, unfolded protein binding and protein folding. | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.897 |
| ANL61329.1 | sodB | AMC85_CH04007 | AMC85_CH01287 | Protein involved in heat shock protein binding, unfolded protein binding and protein folding. | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.884 |
| ANL61329.1 | soxR | AMC85_CH04007 | AMC85_CH04121 | Protein involved in heat shock protein binding, unfolded protein binding and protein folding. | Redox-sensitive transcriptional activator SoxR; Protein involved in DNA binding, sequence-specific DNA binding transcription factor activity, iron ion binding, regulation of transcription, DNA-dependent and response to oxidative stress. | 0.499 |
| ANL61442.1 | soxR | AMC85_CH04120 | AMC85_CH04121 | 3-oxoacyl-(acyl-carrier-protein) reductase protein; Protein involved in nucleotide binding and metabolic process. | Redox-sensitive transcriptional activator SoxR; Protein involved in DNA binding, sequence-specific DNA binding transcription factor activity, iron ion binding, regulation of transcription, DNA-dependent and response to oxidative stress. | 0.582 |
| dnaJ | grpE | AMC85_CH00184 | AMC85_CH00403 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | 0.991 |
| dnaJ | sodB | AMC85_CH00184 | AMC85_CH01287 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.899 |
| dnaJ | soxR | AMC85_CH00184 | AMC85_CH04121 | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | Redox-sensitive transcriptional activator SoxR; Protein involved in DNA binding, sequence-specific DNA binding transcription factor activity, iron ion binding, regulation of transcription, DNA-dependent and response to oxidative stress. | 0.499 |
| grpE | ANL58429.1 | AMC85_CH00403 | AMC85_CH01010 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | DnaJ family heat shock protein; Protein involved in unfolded protein binding and protein folding. | 0.950 |
| grpE | ANL61329.1 | AMC85_CH00403 | AMC85_CH04007 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Protein involved in heat shock protein binding, unfolded protein binding and protein folding. | 0.897 |
| grpE | dnaJ | AMC85_CH00403 | AMC85_CH00184 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] | 0.991 |
| grpE | sodB | AMC85_CH00403 | AMC85_CH01287 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. | 0.578 |
| grpE | soxR | AMC85_CH00403 | AMC85_CH04121 | Heat shock protein GrpE; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- [...] | Redox-sensitive transcriptional activator SoxR; Protein involved in DNA binding, sequence-specific DNA binding transcription factor activity, iron ion binding, regulation of transcription, DNA-dependent and response to oxidative stress. | 0.481 |
| regB | soxR | AMC85_CH00059 | AMC85_CH04121 | Sensor histidine kinase RegB; Protein involved in signal transducer activity and signal transduction. | Redox-sensitive transcriptional activator SoxR; Protein involved in DNA binding, sequence-specific DNA binding transcription factor activity, iron ion binding, regulation of transcription, DNA-dependent and response to oxidative stress. | 0.543 |
| rpoB | ANL58097.1 | AMC85_CH01741 | AMC85_CH00673 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Protein involved in two-component response regulator activity, two-component signal transduction system (phosphorelay) and regulation of transcription, DNA-dependent. | 0.512 |