STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
acsAacetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family. (651 aa)    
Predicted Functional Partners:
gltA
Citrate synthase; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer and cellular carbohydrate metabolic process; Belongs to the citrate synthase family.
  
 0.963
ANL59640.1
Citrate synthase protein; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer and cellular carbohydrate metabolic process.
  
 0.960
citA
Citrate synthase; Protein involved in transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer and cellular carbohydrate metabolic process; Belongs to the citrate synthase family.
  
 0.959
glcB
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
   
 0.958
fadA
acetyl-CoA C-acetyltransferase; Protein involved in transferase activity, transferring acyl groups other than amino-acyl groups and metabolic process; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.944
phbA
acetyl-CoA acetyltransferase; Protein involved in transferase activity, transferring acyl groups other than amino-acyl groups and metabolic process; Belongs to the thiolase-like superfamily. Thiolase family.
  
 
 0.944
fadJ
Fatty acid oxidation complex subunit alpha FadJ; Protein involved in nucleotide binding, oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor, coenzyme binding and oxidation-reduction process.
  
 0.942
pccA
propionyl-CoA carboxylase subunit alpha; Protein involved in ATP binding, ligase activity and metabolic process.
  
 0.941
ackA
Acetate kinase; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family.
   
 
 0.940
iolA
Methylmalonate-semialdehyde dehydrogenase (acylating); Protein involved in oxidoreductase activity, oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor, metabolic process and oxidation-reduction process.
  
 0.931
Your Current Organism:
Rhizobium phaseoli
NCBI taxonomy Id: 396
Other names: ATCC 14482, DSM 30137, IFO 14785, JCM 20683, NBRC 14785, NRRL L-321, R. phaseoli
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