Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF93_08560Delta-aminolevulinic acid dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the ALAD family. (336 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.999
hemL
Glutamate-1-semialdehyde aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.997
BF93_08565
uroporphyrinogen-III synthase; Catalyzes cyclization of the linear tetrapyrrole, hydroxymethylbilane, to the macrocyclic uroporphyrinogen III.
 
 0.962
BF93_00390
uroporphyrin-III methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.956
BF93_08590
Uroporphyrinogen decarboxylase; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.949
hemA
glutamyl-tRNA reductase; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.949
BF93_08585
Protoporphyrinogen oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.893
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.874
BF93_04815
uroporphyrinogen-III synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.827
kbl
2-amino-3-ketobutyrate CoA ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA.
    
 0.803
Your Current Organism:
Brachybacterium phenoliresistens
NCBI taxonomy Id: 396014
Other names: B. phenoliresistens, BCRC 17589, Brachybacterium phenoliresistens Chou et al. 2007, Brachybacterium sp. phenol-A, JCM 15157, LMG 23707, LMG:23707, strain phenol-A
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