| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF93_03185 | BF93_06775 | BF93_03185 | BF93_06775 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.870 |
| BF93_03185 | BF93_08880 | BF93_03185 | BF93_08880 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.891 |
| BF93_03185 | BF93_08885 | BF93_03185 | BF93_08885 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.775 |
| BF93_03185 | BF93_13570 | BF93_03185 | BF93_13570 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.807 |
| BF93_03185 | BF93_14665 | BF93_03185 | BF93_14665 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.416 |
| BF93_03185 | glyA | BF93_03185 | BF93_01235 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.954 |
| BF93_03185 | ilvA | BF93_03185 | BF93_18160 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.915 |
| BF93_03185 | thrB | BF93_03185 | BF93_00065 | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.829 |
| BF93_06775 | BF93_03185 | BF93_06775 | BF93_03185 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.870 |
| BF93_06775 | BF93_08880 | BF93_06775 | BF93_08880 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.896 |
| BF93_06775 | BF93_08885 | BF93_06775 | BF93_08885 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.752 |
| BF93_06775 | BF93_13570 | BF93_06775 | BF93_13570 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.444 |
| BF93_06775 | glyA | BF93_06775 | BF93_01235 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.941 |
| BF93_06775 | ilvA | BF93_06775 | BF93_18160 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.861 |
| BF93_06775 | thrB | BF93_06775 | BF93_00065 | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. | 0.473 |
| BF93_08880 | BF93_03185 | BF93_08880 | BF93_03185 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.891 |
| BF93_08880 | BF93_06775 | BF93_08880 | BF93_06775 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Phosphoserine phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.896 |
| BF93_08880 | BF93_08885 | BF93_08880 | BF93_08885 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.999 |
| BF93_08880 | BF93_13570 | BF93_08880 | BF93_13570 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Catalyzes the formation of cystathionine from L-cysteine and O-succinyl-L-homoserine; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.875 |
| BF93_08880 | BF93_14665 | BF93_08880 | BF93_14665 | Serine acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.935 |