| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| BF93_02240 | BF93_09825 | BF93_02240 | BF93_09825 | Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family. | Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.907 |
| BF93_02240 | BF93_17060 | BF93_02240 | BF93_17060 | Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase M24B family. | 2,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| BF93_04055 | BF93_09825 | BF93_04055 | BF93_09825 | Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.907 |
| BF93_04055 | BF93_17060 | BF93_04055 | BF93_17060 | Xaa-Pro aminopeptidase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.430 |
| BF93_05805 | BF93_06040 | BF93_05805 | BF93_06040 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.676 |
| BF93_05805 | BF93_07360 | BF93_05805 | BF93_07360 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.728 |
| BF93_05805 | BF93_09810 | BF93_05805 | BF93_09810 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family. | 0.994 |
| BF93_05805 | BF93_09825 | BF93_05805 | BF93_09825 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.978 |
| BF93_05805 | BF93_17060 | BF93_05805 | BF93_17060 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 2,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.554 |
| BF93_05805 | gcvH | BF93_05805 | BF93_08850 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.727 |
| BF93_05805 | gcvP | BF93_05805 | BF93_08845 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.876 |
| BF93_05805 | kgd | BF93_05805 | BF93_10070 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.407 |
| BF93_06040 | BF93_05805 | BF93_06040 | BF93_05805 | 1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.676 |
| BF93_06040 | BF93_07360 | BF93_06040 | BF93_07360 | 1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.974 |
| BF93_06040 | BF93_09825 | BF93_06040 | BF93_09825 | 1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family. | 0.950 |
| BF93_06040 | BF93_17060 | BF93_06040 | BF93_17060 | 1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 2,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.746 |
| BF93_06040 | gcvH | BF93_06040 | BF93_08850 | 1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.867 |
| BF93_06040 | gcvP | BF93_06040 | BF93_08845 | 1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.944 |
| BF93_06040 | kgd | BF93_06040 | BF93_10070 | 1-pyrroline-5-carboxylate dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.953 |
| BF93_07360 | BF93_05805 | BF93_07360 | BF93_05805 | Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.728 |