Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
BF93_12910Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (646 aa)    
Predicted Functional Partners:
ribA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
    
  0.786
BF93_05805
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
    
  0.784
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.705
BF93_12905
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.658
BF93_12915
N-acyl homoserine lactonase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.621
BF93_12925
Alcohol dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.552
BF93_12920
FmdB family regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.520
leuS
leucyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
   0.510
BF93_12930
Succinate-semialdehyde dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the aldehyde dehydrogenase family.
       0.504
BF93_01375
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.499
Your Current Organism:
Brachybacterium phenoliresistens
NCBI taxonomy Id: 396014
Other names: B. phenoliresistens, BCRC 17589, Brachybacterium phenoliresistens Chou et al. 2007, Brachybacterium sp. phenol-A, JCM 15157, LMG 23707, LMG:23707, strain phenol-A
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