Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
BF93_16235D-amino acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology. (373 aa)    
Predicted Functional Partners:
BF93_07360
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.908
BF93_17060
2,4-dienoyl-CoA reductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.880
BF93_09825
Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
 
  0.861
BF93_04030
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.817
BF93_04025
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
 
 
  0.816
BF93_16240
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.773
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.735
BF93_05805
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 
 0.731
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.689
BF93_09815
Glycine cleavage system protein T; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
 
  0.682
Your Current Organism:
Brachybacterium phenoliresistens
NCBI taxonomy Id: 396014
Other names: B. phenoliresistens, BCRC 17589, Brachybacterium phenoliresistens Chou et al. 2007, Brachybacterium sp. phenol-A, JCM 15157, LMG 23707, LMG:23707, strain phenol-A
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