| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| KRN58113.1 | KRN58670.1 | IV45_GL000556 | IV45_GL000293 | ATP-dependent chaperone ClpB; Belongs to the ClpA/ClpB family. | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | 0.764 |
| KRN58280.1 | KRN58670.1 | IV45_GL000725 | IV45_GL000293 | ATP-dependent chaperone ClpB; Belongs to the ClpA/ClpB family. | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | 0.764 |
| KRN58587.1 | KRN58670.1 | IV45_GL001037 | IV45_GL000293 | ATP-dependent chaperone ClpB; Belongs to the ClpA/ClpB family. | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | 0.764 |
| KRN58669.1 | KRN58670.1 | IV45_GL000292 | IV45_GL000293 | Hypothetical protein; Belongs to the ArsC family. | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | 0.605 |
| KRN58669.1 | KRN58671.1 | IV45_GL000292 | IV45_GL000294 | Hypothetical protein; Belongs to the ArsC family. | Competence protein. | 0.635 |
| KRN58669.1 | KRN59164.1 | IV45_GL000292 | IV45_GL000202 | Hypothetical protein; Belongs to the ArsC family. | Replicative DNA helicase loader DnaI. | 0.539 |
| KRN58669.1 | rpoE | IV45_GL000292 | IV45_GL001401 | Hypothetical protein; Belongs to the ArsC family. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.648 |
| KRN58670.1 | KRN58113.1 | IV45_GL000293 | IV45_GL000556 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | ATP-dependent chaperone ClpB; Belongs to the ClpA/ClpB family. | 0.764 |
| KRN58670.1 | KRN58280.1 | IV45_GL000293 | IV45_GL000725 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | ATP-dependent chaperone ClpB; Belongs to the ClpA/ClpB family. | 0.764 |
| KRN58670.1 | KRN58587.1 | IV45_GL000293 | IV45_GL001037 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | ATP-dependent chaperone ClpB; Belongs to the ClpA/ClpB family. | 0.764 |
| KRN58670.1 | KRN58669.1 | IV45_GL000293 | IV45_GL000292 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | Hypothetical protein; Belongs to the ArsC family. | 0.605 |
| KRN58670.1 | KRN58671.1 | IV45_GL000293 | IV45_GL000294 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | Competence protein. | 0.732 |
| KRN58670.1 | KRN59071.1 | IV45_GL000293 | IV45_GL000107 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | Primosome. | 0.651 |
| KRN58670.1 | KRN59164.1 | IV45_GL000293 | IV45_GL000202 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | Replicative DNA helicase loader DnaI. | 0.590 |
| KRN58670.1 | KRN59184.1 | IV45_GL000293 | IV45_GL000222 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | Penicillin-binding protein 2A. | 0.735 |
| KRN58670.1 | rpoE | IV45_GL000293 | IV45_GL001401 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | DNA-directed RNA polymerase, delta subunit; Participates in both the initiation and recycling phases of transcription. In the presence of the delta subunit, RNAP displays an increased specificity of transcription, a decreased affinity for nucleic acids, and an increased efficiency of RNA synthesis because of enhanced recycling; Belongs to the RpoE family. | 0.634 |
| KRN58670.1 | smpB | IV45_GL000293 | IV45_GL001266 | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | ssrA-binding protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] | 0.705 |
| KRN58671.1 | KRN58669.1 | IV45_GL000294 | IV45_GL000292 | Competence protein. | Hypothetical protein; Belongs to the ArsC family. | 0.635 |
| KRN58671.1 | KRN58670.1 | IV45_GL000294 | IV45_GL000293 | Competence protein. | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | 0.732 |
| KRN59071.1 | KRN58670.1 | IV45_GL000107 | IV45_GL000293 | Primosome. | Competence negative regulator; Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis; Belongs to the MecA family. | 0.651 |
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